The association of depressive symptoms, personality traits, and sociodemographic factors with health-related quality of life and quality of life in patients with advanced-stage lung cancer: an observational multi-center cohort study

Table 1 Characteristics of study population

Characteristic	Patients who completed questionnaires (N = 151)	Patients who did not complete any questionnaire (N = 26)	P_a
Age, years_b
Mean (SD)	63.3 (9.1)	63.7 (8.7)	0.85
Min, max	37, 83	47, 80
Gender
Male	82 (54.3)	12 (46.2)	0.53
Ethnicity
White / Caucasian	142 (94.0)	25 (96.2)	1.00
Other	9 (6.0)	1 (3.8)
Education_c
Low	113 (74.8)
High	32 (21.2)
Unknown	1 (0.7)	26 (100.0)
Employment_b
Yes	38 (25.2)	1 (3.8)	0.26
No	112 (74.2)
Unknown	1 (0.7)	25 (96.2)
Partner status_b
Partner	122 (80.8)	1 (3.8)	1.00
No partner	28 (18.5)
Unknown	1 (0.7)	25 (96.2)
Cancer stage_b
Locally advanced (IIIB)	19 (12.6)	2 (7.7)	0.76
Metastatic (IV)	124 (82.1)	23 (88.5)
Other	8 (5.3)	1 (3.8)
Type of tumor_b
Adenocarcinoma	136 (90.1)	24 (92.3)	1.00
Large cell carcinoma, mesothelioma, other	15 (9.9)	2 (7.7)
Line of therapy
irst	140 (92.7)	22 (84.6)	0.24
econd	11 (7.3)	4 (15.4)
ECOG performance status_b
Grade 0 or 1	135 (89.4)	18 (69.2)	0.02
Grade 2 or higher	14 (9.3)	7 (26.9)
Unknown	2 (1.3)	1 (3.8)

Values are given in numbers (percentages) unless stated otherwise. _aP-values reflect differences between patients who completed any questionnaire and those who did not
_bMeasured at the start of treatment with chemotherapy
_cLow education: persons whose highest level of education is primary education, lower general education or lower vocational education. High education: persons whose highest level of education is higher general education, higher vocational education or university.
Abbreviations: N number of patients, SD standard deviation, ECOG Eastern Cooperative Oncology Group (ECOG)

ISSN: 1471-2407