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Table 2 Definitions and distributions of the eight quantitative volumetric, kinetic, and clinical variables used in this investigation

From: Sex-specific impact of patterns of imageable tumor growth on survival of primary glioblastoma patients

Variable used for InvestigationDefinitionMaleFemale
MeanMedianRangeMeanMedianRange
Age
(years)
Age of patient on date of diagnosis57.585812–9558.4160.59–96
T1Gd Radius
(mm)
Combined volume of the central non-enhancing necrotic region and surrounding enhanced region of tumor in a pre-tx T1Gd MR image (converted to a spherically- equivalent radius)19.5220.103.04–33.6119.2718.994.61–35.08
Necrosis Radius (mm)Volume of non-enhancing central necrotic region in a pre-tx T1Gd MR image (converted to a spherically- equivalent radius)11.3911.690.00–26.5411.3711.330.00–27.06
Contrast- enhancing (CE) thickness (mm)Average linear thickness of the contrast-enhancing region in a pre-tx T1Gd MR image (calculated as the difference between the T1Gd radius and the necrosis radius)8.167.852.55–18.947.897.590.32–23.26
T2 /FLAIR radius (mm)Volume of the pre-tx T2 or T2-FLAIR MR image (converted to a spherically- equivalent radius)27.1128.319.94–39.5526.9827.869.99–42.81
PIHNA D (mm2/year)Net tumor cell diffuse invasion rate32.3428.991.45–145.336.2523.030.37–289.9
PIHNA ϱ (year −1)Net tumor cell proliferation rate65.8818.251.83–182582.4018.251.83–1825
PI D/ϱ (mm2)Relative tumor invasiveness2.191.650.0034–10.262.121.280.0034–10.70