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Table 4 Prognostic factors associated with overall mortality after EBRT

From: Both comorbidity and worse performance status are associated with poorer overall survival after external beam radiotherapy for prostate cancer

Model 1.Charlson Comorbidity Index used as categorical variant.

Factor

HR

95-% CI

P-value

CCI = 0 (N = 298)

  

< 0.001

CCI = 1–3 (N = 324)

1.38

[0.97–1.97]

0.078 (NS)

CCI = 4 or more (N = 42)

6.11

[3.76–9.92]

< 0.001

Gleason score

1.21

[1.04–1.41]

0.015

T-grade

1.11

[1.01–1.21]

0.030

Zubrod score

1.63

[1.29–2.05]

< 0.001

Not significant: Androgen deprivation therapy (P = 0.70), age (P = 0.27), N-grade (P = 0.75), PSA-value before diagnosis (P = 0.15).

Model 2.Performance status used as categorical variant.

Z = 0 (N = 348)

  

<  0.001

Z = 1 (N = 281)

2.20

[1.54–3.13]

<  0.001

Z = 2 or more (N = 36)

2.22

[1.21–4.09]

0.010

Charlson Comorbidity Index

1.38

[1.25–1.51]

<  0.001

Gleason score

1.19

[1.02–1.39]

0.026

T-grade

1.11

[1.02–1.22]

0.022

  1. Not significant: Androgen deprivation therapy (P = 0.88), age (P = 0.18), N-grade (P = 0.77), PSA-value before diagnosis (P = 0.080)
  2. N = 665. Abbreviations: NS not significant, HR hazard ratio, CI confidence interval