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Table 4 Prognostic factors associated with overall mortality after EBRT

From: Both comorbidity and worse performance status are associated with poorer overall survival after external beam radiotherapy for prostate cancer

Model 1.Charlson Comorbidity Index used as categorical variant.
FactorHR95-% CIP-value
CCI = 0 (N = 298)  < 0.001
CCI = 1–3 (N = 324)1.38[0.97–1.97]0.078 (NS)
CCI = 4 or more (N = 42)6.11[3.76–9.92]< 0.001
Gleason score1.21[1.04–1.41]0.015
T-grade1.11[1.01–1.21]0.030
Zubrod score1.63[1.29–2.05]< 0.001
Not significant: Androgen deprivation therapy (P = 0.70), age (P = 0.27), N-grade (P = 0.75), PSA-value before diagnosis (P = 0.15).
Model 2.Performance status used as categorical variant.
Z = 0 (N = 348)  <  0.001
Z = 1 (N = 281)2.20[1.54–3.13]<  0.001
Z = 2 or more (N = 36)2.22[1.21–4.09]0.010
Charlson Comorbidity Index1.38[1.25–1.51]<  0.001
Gleason score1.19[1.02–1.39]0.026
T-grade1.11[1.02–1.22]0.022
  1. Not significant: Androgen deprivation therapy (P = 0.88), age (P = 0.18), N-grade (P = 0.77), PSA-value before diagnosis (P = 0.080)
  2. N = 665. Abbreviations: NS not significant, HR hazard ratio, CI confidence interval