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Fig. 3 | BMC Cancer

Fig. 3

From: Intranasal perillyl alcohol therapy improves survival of patients with recurrent glioblastoma harboring mutant variant for MTHFR rs1801133 polymorphism

Fig. 3

a Multiple comparison of gDNA hypermethylation median levels according rs1801133 variants (d = 0.751) show that rGBM patients harboring the TT genotype variant presented a significant and marked reduction (1.2-fold) on gDNA hypermethylation (median = 112.02%) when compared to CC (median = 132.45%, d = 0.979) and CT (median = 137.80%,d = 1.167) genotypes. Significant, moderate and negative correlations between TT or CC (rho = − 0.450; p = 0.040, figure 3b) genotypes, and TT or CT (rho = − 0.518; p = 0.023, figure 3c) variants and global gDNA hypermethylation levels

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BMC Cancer

ISSN: 1471-2407

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