Fig. 1From: Characterization of LGR5 expression in poorly differentiated colorectal carcinoma with mismatch repair protein deficiencyRepresentative images and staining of MMR-P and MMR-D cases. Representative features in MMR-D (a) and MMR-P (f). Immunohistochemistry of four MMR proteins. Loss of MLH1/PMS2 (b and c) and expression of MSH2/MSH6 (d and e) are shown in MMR-D. All four MMR proteins (g, h, i, and j) are detected in MMR-P. (a and f, HE; b and g, MLH1 immunostaining; c and h, PMS2 immunostaining; d and i, MSH2 immunostaining; e and j, MSH6 immunostaining)Back to article page