Fig. 4

Mutational landscape of 729 tumor samples, which were analyzed with the PATH panel in routine diagnostics. (Likely) pathogenic mutations, variants of unknown significance, amplifications, and MSI status are depicted in the figure. Tumor samples are sorted on genetic alterations, followed by tumor type, and MSI status. Each column represents a tumor sample. Each row represents a genetic alterations (i.e. mutation (light red, red, or dark red), CNV (cyan), or MSI (light red). A colored bar represents a genetic alterations, a white bar represents no alteration, and a grey bar represents not analyzed. The top row shows the tumor types of the analyzed samples: lung cancer (dark blue), colorectal cancer (light blue), melanoma (dark green), GIST (light green), or miscellaneous (black)