Fig. 6

miRNA-mRNA interaction networks for right and left-sided colon cancers. a. Select clusters extracted from RSCC interaction network, with several uniquely regulated miRs (orange) are involved in regulating genes associated with cell cycle control. b. A cluster extracted from LSCC, containing the miR-29 (miR-29a and miR-29a) indicates a possible role for these miRNAs in regulating the interaction between period genes and ECM markers. c and d indicate the cluster containing miR-34a and miR-22 extracted for RSCC and LSCC respectively. Node color: Blue- downregulated, red- upregulated, green- commonly regulated miR and orange- uniquely regulated miR. miR label color: red- upregulated, blue- downregulated