Fig. 2

a Pathway heat map for 66 selected KEGG pathways where each pathway is significantly perturbed in at least 80% of the studies in one or both of the two groups of cancer. Green indicates down-regulation of pathway, red indicates up-regulation. In the column-sidebar, purple indicates SS group, cyan indicates SLC group and blue indicates CA group. Positive pathway score is presented in red, negative pathway score in green. b Box plot shows group-mean pathway scores for the three groups of diseases. In general, there is pathway up-regulation in the SLC group, even higher than that in SS, while down-regulation in CA group. This figure was generated using R programming language (Version 3.4.4) and GIMP (Version 2.8.22)