3rd month QoL change % | 6th month QoL change % | |||||
---|---|---|---|---|---|---|
Gemcitabine | Gemcitabine + nab-Paclitaxel | p | Gemcitabine | Gemcitabine + nab-Paclitaxel | p | |
Mean | Mean | Mean | Mean | |||
Functional scales | ||||||
Cognitive functioning | −8.8 | 23.8 | 0.048 | 21 | 22.5 | 0.387 |
Emotional functioning | 12.9 | 50.8 | 0.048 | 0.6 | 37.8 | 0.851 |
Physical functioning | −11.7 | 12.8 | 0.051 | −4.9 | 5.7 | 0.761 |
Role functioning | 2.9 | 17.4 | 0.039 | 42.3 | 10.9 | 0.456 |
Social functioning | −1.6 | 30.4 | 0.024 | 7.5 | 3.9 | 0.743 |
Symptom scales | ||||||
Appetite loss | −12.5 | −14.4 | 0.226 | −13.3 | − 15 | 0.771 |
Constipation | 14.1 | 25.9 | 0.706 | 22.9 | 8.6 | 0.888 |
Diarrhea | 2.6 | 17.6 | 0.558 | 16.9 | −1.4 | 0.707 |
Dyspnea | −32.6 | −7.4 | 0.172 | 11 | −17.6 | 0.206 |
Fatigue | 60.4 | 5.9 | 0.027 | −51.4 | −30.4 | 0.924 |
Financial difficulties | −11 | 12.1 | 0.077 | −13.8 | 12.8 | 0.879 |
Insomnia | −19 | 11 | 0.141 | −9.6 | 7.7 | 0.276 |
Nausea-vomiting | −4.1 | 12 | 0.559 | −0.6 | −0.8 | 0.898 |
Pain | −13.8 | 12.4 | 0.142 | −11.3 | − 16.6 | 0.514 |
Global health status/QoL | 12.7 | 8 | 0.163 | 70.6 | −9.2 | 0.158 |