Fig. 2

Sequential t-SNE analysis of SARC and KIRP. a. t-SNE-generated patterns of SARC Myc Pathway transcripts showing two distinct clusters. b. Kaplan-Meier survival curves of each of the tSNE clusters depicted in A. c. t-SNE analysis of SARC TGF-β Pathway transcripts. d. Kaplan-Meier survival curves of patients from each of the clusters shown in C. e. Kaplan-Meier curves of patients from the unfavorable survival TGF-β Pathway cluster from C after t-SNE analysis with Myc Pathway transcripts. Two t-SNE clusters similar to those depicted in A were generated (not shown). F. Kaplan-Meier survival of patients from the favorable survival TGF-β Pathway cluster shown in C after t-SNE analysis with Myc Pathway transcripts. Two t-SNE groups similar to those shown in A were generated (not shown). g. t-SNE analysis of KIRP Cell Cycle Pathway transcripts showing two major tumor clusters and a third comprised of only seven tumors. h. Kaplan-Meier survival curves of patients from Clusters 1 and 2 depicted in G. i. t-SNE-generated patterns of KIRP Pentose Phosphate Pathway transcripts showing two major clusters. j Kaplan-Meier survival curves of each of patients from the tumor clusters depicted in I. k. Kaplan-Meier curves of individuals from the unfavorable survival Pentose Phosphate Pathway cluster from I after t-SNE analysis using transcripts from the Cell Cycle Pathway. Two t-SNE clusters similar to those depicted in A were generated (not shown). l. Kaplan-Meier curves of individuals from the favorable survival Pentose Phosphate Pathway cluster from K after t-SNE analysis using transcripts from the Myc Pathway. Two t-SNE clusters similar to those depicted in A were generated (not shown)