Table 4 Summary of literatures reporting PD-1, PD-L1, and PD-L2 expression in primary central nervous system lymphoma
PD-1 | PD-L1 | PD-L2 | |||
|---|---|---|---|---|---|
TIC | TC | TIC | TC | TIC | |
Berghoff AS, Clin Neuropath 2014 | 12/20 (60%) | 2/20 (10%) | 4/20 (20%) | ||
Hayano A, Anticancer Res 2017 | 2/48 (4.1%) | 25/48 (52%) | |||
Cho H, Oncotarget 2017 | 35/76 (46.1%) | 54/76 (71.1%) | 64/76 (84.2%) | ||
Sugita Y, Neuropathology 2018 | |||||
EBV (+) | 12/17 (71%) | 16/17 (94%) | |||
EBV (−) | 11/22 (50%) | 11/22 (50%) | |||
This study | 19/70 (27.1%) | 68/70 (97.1%) | 3/70 (4.3%) | 66/70 (94.3%) | |