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Table 1 Patient demographics

From: PD-L1 and PD-L2 expression in the tumor microenvironment including peritumoral tissue in primary central nervous system lymphoma

  

Subgroup of biopsy methods

 
 

All cases (n = 70)

Needle biopsy (n = 28)

Craniotomy (n = 42)

p value

Median age (years)

67.5

68.5

67.0

0.8761

Sex, male (%)

38 (54.3)

19 (67.9)

19 (45.2)

0.0627

Median KPS

70

60

80

0.1368

Existence of deep-seated lesion (%)

51 (73.9)

25 (89.3)

26 (51.0)

0.0163

Case with multiple lesions (%)

35 (50.7)

17 (60.7)

18 (43.9)

0.1702

Case with elevated LDH (%)

17 (25.8)

5 (19.2)

12 (30.0)

0.3283

MSKCC score

 Class 1 (age ≤ 50 yrs) (%)

6 (8.8)

3 (11.1)

4 (9.8)

0.0226

 Class 2 (age > 50 yrs., KPS ≥ 70) (%)

36 (52.9)

9 (33.3)

27 (65.8)

 

 Class 3 (age > 50 yrs., KPS < 70) (%)

26 (38.2)

15 (55.6)

10 (24.4)

 

Extent of resection

 Gross total resection (%)

11 (15.9)

0 (0.0)

11 (26.8)

< 0.0001

 Partial removal (%)

24 (34.8)

0 (0.0)

24 (58.5)

 

 Biopsy (%)

34 (49.3)

28 (100.0)

6 (14.6)

 

Chemotherapy (%)

60 (87.0)

28 (100.0)

32 (78.1)

0.0078

Radiotherapy (%)

48 (69.6)

17 (60.7)

31 (75.6)

0.1867

  1. KPS Karnofsky performance status, MSKCC Memorial Sloan Kettering Cancer Center