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Table 4 The functional analyses of survival-related genes

From: A novel risk score model based on eight genes and a nomogram for predicting overall survival of patients with osteosarcoma

CategoryTermCountP valueFDR
GO-BPGO:0002250~adaptive immune response286.430E-131.560E-09
GO:0050776~regulation of immune response285.700E-116.900E-08
GO:0070098~chemokine-mediated signaling pathway181.450E-101.170E-07
GO:0006955~immune response413.820E-091.850E-06
GO:0042110~T cell activation143.170E-091.920E-06
GO:0006935~chemotaxis191.430E-075.750E-05
GO:0006954~inflammatory response352.300E-077.950E-05
GO:0006968~cellular defense response139.040E-072.730E-04
GO:0007267~cell-cell signaling261.760E-064.740E-04
GO:0007166~cell surface receptor signaling pathway272.180E-065.280E-04
GO:0071346~cellular response to interferon-gamma111.840E-054.037E-03
GO:0042102~positive regulation of T cell proliferation112.930E-055.894E-03
GO:0007204~positive regulation of cytosolic calcium ion concentration164.730E-058.769E-03
GO:0035589~G-protein coupled purinergic nucleotide receptor signaling pathway66.700E-051.152E-02
GO:0043547~positive regulation of GTPase activity389.630E-051.446E-02
GO:0070374~positive regulation of ERK1 and ERK2 cascade189.260E-051.484E-02
GO:0007155~cell adhesion322.060E-042.894E-02
GO:0007165~signal transduction632.210E-042.926E-02
GO:0048247~lymphocyte chemotaxis72.880E-043.606E-02
GO:0042472~inner ear morphogenesis93.260E-043.873E-02
GO:0050850~positive regulation of calcium-mediated signaling64.390E-044.712E-02
GO:0006508~proteolysis334.240E-044.774E-02
GO:0002548~monocyte chemotaxis84.660E-044.781E-02
KEGG Pathwayhsa04060:Cytokine-cytokine receptor interaction384.250E-129.690E-10
hsa04080:Neuroactive ligand-receptor interaction344.100E-084.680E-06
hsa04640:Hematopoietic cell lineage174.960E-073.770E-05
hsa04514:Cell adhesion molecules (CAMs)192.440E-051.389E-03
hsa04062:Chemokine signaling pathway219.560E-054.350E-03
hsa04660:T cell receptor signaling pathway139.200E-042.590E-02
hsa05033:Nicotine addiction81.213E-033.028E-02
hsa04650:Natural killer cell mediated cytotoxicity141.739E-033.543E-02
  1. KEGG Kyoto Encyclopedia of Genes and Genomes, FDR false discovery rate,  GO-BP Gene Ontology-Biology Process