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Table 4 The functional analyses of survival-related genes

From: A novel risk score model based on eight genes and a nomogram for predicting overall survival of patients with osteosarcoma

Category

Term

Count

P value

FDR

GO-BP

GO:0002250~adaptive immune response

28

6.430E-13

1.560E-09

GO:0050776~regulation of immune response

28

5.700E-11

6.900E-08

GO:0070098~chemokine-mediated signaling pathway

18

1.450E-10

1.170E-07

GO:0006955~immune response

41

3.820E-09

1.850E-06

GO:0042110~T cell activation

14

3.170E-09

1.920E-06

GO:0006935~chemotaxis

19

1.430E-07

5.750E-05

GO:0006954~inflammatory response

35

2.300E-07

7.950E-05

GO:0006968~cellular defense response

13

9.040E-07

2.730E-04

GO:0007267~cell-cell signaling

26

1.760E-06

4.740E-04

GO:0007166~cell surface receptor signaling pathway

27

2.180E-06

5.280E-04

GO:0071346~cellular response to interferon-gamma

11

1.840E-05

4.037E-03

GO:0042102~positive regulation of T cell proliferation

11

2.930E-05

5.894E-03

GO:0007204~positive regulation of cytosolic calcium ion concentration

16

4.730E-05

8.769E-03

GO:0035589~G-protein coupled purinergic nucleotide receptor signaling pathway

6

6.700E-05

1.152E-02

GO:0043547~positive regulation of GTPase activity

38

9.630E-05

1.446E-02

GO:0070374~positive regulation of ERK1 and ERK2 cascade

18

9.260E-05

1.484E-02

GO:0007155~cell adhesion

32

2.060E-04

2.894E-02

GO:0007165~signal transduction

63

2.210E-04

2.926E-02

GO:0048247~lymphocyte chemotaxis

7

2.880E-04

3.606E-02

GO:0042472~inner ear morphogenesis

9

3.260E-04

3.873E-02

GO:0050850~positive regulation of calcium-mediated signaling

6

4.390E-04

4.712E-02

GO:0006508~proteolysis

33

4.240E-04

4.774E-02

GO:0002548~monocyte chemotaxis

8

4.660E-04

4.781E-02

KEGG Pathway

hsa04060:Cytokine-cytokine receptor interaction

38

4.250E-12

9.690E-10

hsa04080:Neuroactive ligand-receptor interaction

34

4.100E-08

4.680E-06

hsa04640:Hematopoietic cell lineage

17

4.960E-07

3.770E-05

hsa04514:Cell adhesion molecules (CAMs)

19

2.440E-05

1.389E-03

hsa04062:Chemokine signaling pathway

21

9.560E-05

4.350E-03

hsa04660:T cell receptor signaling pathway

13

9.200E-04

2.590E-02

hsa05033:Nicotine addiction

8

1.213E-03

3.028E-02

hsa04650:Natural killer cell mediated cytotoxicity

14

1.739E-03

3.543E-02

  1. KEGG Kyoto Encyclopedia of Genes and Genomes, FDR false discovery rate,  GO-BP Gene Ontology-Biology Process