Skip to main content

Table 3 The univariables and multi-variables cox regression of clinical parameters and survival outcomes of patients with osteosarcoma

From: A novel risk score model based on eight genes and a nomogram for predicting overall survival of patients with osteosarcoma

Clinical characteristicsTCGA(N = 176)Uni-variables coxMulti-variables cox
HR95%CIPHR95%CIP
Age(years, mean ± sd)61.01 ± 15.231.0180.999–1.0365.19E-02
Gender(Male/Female)72/1041.1020.666–1.8277.05E-01
Pathologic tumor depth(years, mean ± sd)6.35 ± 3.691.1360.951–1.2279.05E-02
Pathologic tumor length(years, mean ± sd)11.76 ± 7.251.0610.993–1.0925.91E-02
Pathologic tumor width(years, mean ± sd)8.78 ± 5.511.0910.940–1.1432.17E-01
Tumor multifocal(Yes/No/−)34/132/101.6850.949–2.9917.13E-02
Tumor recurrence(Yes/No/−)28/141/72.6921.581–4.5851.48E-041.6260.914–2.8939.80E-02
Tumor metastatic(Yes/No/−)58/1182.8981.754–4.7891.36E-051.8791.079–3.2742.58E-02
Radiotherapy(Yes/No/−)64/110/20.7990.474–1.3473.99E-01
Tumor necrosis(No/Slight/Moderate/Severe/−)61/35/59/10/111.1910.925–1.5301.75E-01
RS model status(High/ Low)88/883.131.824–5.3701.28E-052.2881.291–4.0574.60E-03
Dead(Death/Alive/−)63/113
Overall survival time(months, mean ± sd)39.76 ± 32.24
  1. SD Standard deviation, HR Hazard ratio, 95%CI 95% confidence interval,  TCGAThe Cancer Genome Atlas