Fig. 2

Volcano plot and heatmap clustering of differentially expressed genes (DEGs). a: Volcano plot of DEGs. The green nodes represent DEGs; the red horizontal dashed lines show the false discovery rate (FDR) value is less than 0.05 and the red vertical dashed lines indicate the value of |log₂ fold change (FC)| is more than 0.5. b: Heatmap clustering of DEGs. The white bars represent metastatic osteosarcoma samples and black bars represent non-metastatic osteosarcoma samples