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Fig. 1 | BMC Cancer

Fig. 1

From: RNAseq expression patterns of canine invasive urothelial carcinoma reveal two distinct tumor clusters and shared regions of dysregulation with human bladder tumors

Fig. 1

Canine iUC tumors cluster into two distinct groups. a) Principal component analysis divides normal from tumor tissues. b) After removing the normal tissues, the first principal component separates tumors with BRAFV595E mutations from those that do not carry the mutation. c) Consensus clustering based on expression data shows two clusters of tumors. Horizontal line under dendrogram: light blue = BRAFV595E tumors, dark blue = BRAFwt tumors. Heatmap blue shades from light to dark with increased confidence. d) Distribution of Jaccard similarity scores among BRAFV595E tumors (coral), BRAFwt tumors (light blue) and between the two mutation types (green)

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