Construction of an integrated human osteosarcoma database, HOsDb, based on literature mining, microarray analysis, and database retrieval

Table 2 Results of data collection and analysis

	Tumor vs. normal	Metastasis vs. non-metastasis	Drug-treated vs. untreated
OS-related gene
DEG (mRNA expression microarray)	6964	685	1589
Known gene (text mining)	505	87	–
Total OS-related gene	7191	763	1589
Gene-TF pair (database)	190,362	21,131	41,135
Gene-miRNA pair (database)	3,749,490	358,361	767,674
Gene-SNP (database)	28,386	2532	3943
OS-related miRNA
DEM (miRNA expression microarray)	209	–	–
miRNA (database)	31	–	–
Total OS-related miRNA	240
OS-related CNV
CNV (CGH microarray)	1695	–	–
OS-related methylation
Gene methylation (database)	18	–	–

OS Osteosarcoma, DEG Differentially expressed gene, DEM Differentially expressed miRNA, miRNA microRNA, CNV Copy number variation, CGH Comparative genomic hybridization

ISSN: 1471-2407