Hypoxic induction of vasculogenic mimicry in hepatocellular carcinoma: role of HIF-1 α, RhoA/ROCK and Rac1/PAK signaling

Table 2 Protein expression of HIF-1α and Vimentin in HCC cancer tissues and adjacent normal tissues

Tissue sample	No. of patients	HIF-1α		P-value	Vimentin		P-value
Tissue sample	No. of patients	Low (%)	High (%)	P-value	Low (%)	High (%)	P-value
Tumor	77	34(44.2)	43(55.8)	0.000*	27(35.1)	50(64.9)	0.000*
Non-cancerous tissues	77	66(85.7)	11(14.3)	0.000*	64 (83.1)	13(16.9)	0.000*

HIF-1α and Vimentin expression was measured in tumor and non-cancerous tissues. Both HIF-1α and Vimentin was higher in tumor tissues compared with non-cancerous tissues. Data were analyzed using the Chi-squared test
*P < 0.05 indicates statistical significance

ISSN: 1471-2407