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Table 1 Mutations detected both in GCT and AML

From: TP53 and PTEN mutations were shared in concurrent germ cell tumor and acute megakaryoblastic leukemia

GeneAccession no.ChraExonNucleotide changeAmino acid changeMutation typeVAF in GCTVAF in AML
ASF1ANM_01403463c.T231Ap.D77Enonsynonymous SNVb0.3240.036
DLG2NM_001142699114c.C140Tp.T47Inonsynonymous SNV0.4680.215
EDRF1NM_0012024381022c.C3172Tp.H1058Ynonsynonymous SNV0.2590.093
GOLGA8JNM_0012824721512c.G992Ap.R331Hnonsynonymous SNV0.1810.095
PCLONM_014510713c.T13947Gp.H4649Qnonsynonymous SNV0.2430.119
PTENNM_000314105c.492ā€‰+ā€‰1Gā€‰>ā€‰Ap.V85Gfs*14splicing0.4760.207
RLFNM_01242118c.4563_4567delp.I1521fsframeshift deletion0.3570.218
TP53NM_000546178c.G836Ap.G279Enonsynonymous SNV0.4810.176
YY2NM_206923X1c.G813Ap.M271Inonsynonymous SNV0.6140.176
  1. Details of mutated genes in both germ cell tumor (GCT) and acute myeloid leukemia (AML). a Chr Chromosome; b SNV Single nucleotide variant