Table 1 The expression of the NER proteins in different histological subtypes of primary GCTs (n = 207)
From: Increased levels of XPA might be the basis of cisplatin resistance in germ cell tumours
| Â | Â | ERCC1 | XPF | XPA | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histological subtype | N | Mean HS | SEM | Median | p valuea | Mean HS | SEM | Median | p value | Mean HS | SEM | Median | p value |
Normal testis | 49 | 0.0 | 0.0 | 0 | NA | 29.4 | 7.0 | 0 | NA | 0.0 | 0.0 | 0 | NA |
Germ cell tumoursb | 207 | 13.5 | 2.9 | 0.0 | <  0.01 | 213.4 | 6.2 | 220.0 | <  0.01 | 51.6 | 4.5 | 20.0 | <  0.01 |
Seminoma | 64 | 2.2 | 1.6 | 0 | <  0.01 | 182.1 | 12.4 | 200 | <  0.01 | 41.4 | 7.3 | 10 | <  0.01 |
Embryonal carcinoma | 118 | 2.2 | 0.9 | 0 | <  0.01 | 224.0 | 6.9 | 220 | <  0.01 | 19.9 | 3.4 | 0 | <  0.01 |
Yolk sac tumour | 30 | 14.0 | 6.7 | 0 | <  0.01 | 202.4 | 20.4 | 210 | <  0.01 | 87.4 | 15.0 | 50 | <  0.01 |
Choriocarcinoma | 15 | 15.3 | 7.1 | 0 | <  0.01 | 181.7 | 24.1 | 200 | <  0.01 | 53.8 | 16.2 | 50 | <  0.01 |
Teratoma | 41 | 56.0 | 11.6 | 20 | <  0.01 | 186.9 | 13.2 | 180 | <  0.01 | 103.4 | 10.6 | 90 | <  0.01 |
GCNIS | 71 | 4.3 | 4.2 | 0 | <  0.01 | 193.1 | 13.0 | 200 | <  0.01 | 7.6 | 3.3 | 0 | <  0.01 |