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Table 1 Expression of NLRP3, Caspase-1 and GSDMD in endometrial tissue by IHC

From: Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway

 

Expression/Cases

Endometrial cancer

Atypical hyperplasia

Benign endometrium

NLRP3

Negative/weak positive

2

0

4

Medium positive

3

1

1

Strong positive

10

2

1

Caspase-1

Negative/weak positive

3

0

6

Medium positive

5

1

0

Strong positive

7

2

0

GSDMD

Negative/weak positive

2

1

4

Medium positive

5

1

1

Strong positive

8

1

1

IL-1β

Negative/weak positive

11

1

3

Medium positive

2

1

1

Strong positive

1

1

2