Skip to main content

Table 6 Haplotypic analysis of ESR1, ESR2, and UGT1A4 polymorphisms

From: Association between ESR1, ESR2, HER2, UGT1A4, and UGT2B7 polymorphisms and breast Cancer in Jordan: a case-control study

HaplotypeFrequency of blockFrequency ratio (case:control)
(%)
Odds ratio
(95% CI)
P-value
ESR1 and ESR2 Block (rs3020410, rs3798577, rs1256049, rs2234693, and rs9340799)
 CTCCG0.24170.2761: 0.2321:00N.A
 CTCTA0.23580.2172: 0.23450.90 (0.56–1.45)0.66
 CCCCG0.19570.2025: 0.16810.61 (0.35–1.04)0.071
 CCCTA0.17020.2008: 0.15380.65 (0.42–1.02)0.061
 ACCTA0.03550.0266: 0.03910.73 (0.27–1.94)0.53
 ATCTA0.03550.0414: 0.03821.16 (0.46–2.89)0.76
 CCCCA0.02770.0291: 0.02740.80 (0.31–2.04)0.64
 CTCCA0.01860.0168: 0.01940.81 (0.22–2.92)0.74
Global haplotype association p-value: 0.47
UGT1A4 Block (rs12468274, rs2011425, and rs6755571)
  TTC0.85520.8557:0.85481.00N.A
  CGC0.07710.0726: 0.08161.12 (0.65–1.92)0.69
  TTA0.05260.0501:0.05511.07 (0.59–1.95)0.82
  TGC0.01180.019: 0.00480.25 (0.05–1.21)0.086
Global haplotype association p-value: 0.39