Association between ESR1, ESR2, HER2, UGT1A4, and UGT2B7 polymorphisms and breast Cancer in Jordan: a case-control study

Table 1 Minor allele frequencies of gene polymorphisms in breast cancer patients and healthy controls

Gene	SNP ID	Cases (n = 218)			Controls (n = 219)
Gene	SNP ID	MA_a	MAF_b	HWE_c p-value	MA_a	MAF_b	HWE_c p-value
ESR1	rs3020410	A	0.1	0.44	A	0.08	0.63
	rs3798577	C	0.41	0.33	C	0.48	0.68
	rs2234693	T	0.49	0.34	T	0.49	0.03
	rs9340799	G	0.47	0.5	G	0.46	0.02
ESR2	rs1256049	T	0.02	1	T	0.02	1
HER2	rs1058808	C	0.32	0.76	C	0.32	0.21
UGT1A4	rs12468274	C	0.08	0.37	C	0.07	0.61
	rs2011425	G	0.09	0.23	G	0.09	0.38
	rs6755571	A	0.06	0.54	A	0.05	0.11
UGT2B7	rs28365062	G	0.16	0.2	G	0.17	0.47
UGT2B7	rs4348159	T	0.16	0.13	T	0.17	0.13

^aMA: minor allele. ^bMAF: minor allele frequency. ^cHWE: Hardy—Weinberg equilibrium. N/A not applicable

ISSN: 1471-2407