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Table 1 Associations between plasma HSP90α levels and clinical characteristics of HCC patients

From: Diagnostic value of plasma HSP90α levels for detection of hepatocellular carcinoma

Clinico-pathological characteristics

 

N (659)

HSP90α (ng/mL)

P

Age (years)

< 50

296

162.56 ± 8.22

0.001

≥50

363

129.02 ± 5.96

Gender

Male

568

145.70 ± 5.45

0.419

Female

91

134.02 ± 11.91

BCLC stage

A

196

85.07 ± 5.03

0.000

B

136

108.11 ± 6.47

C

309

189.91 ± 8.33

D

18

271.84 ± 44.75

AFP (ng/mL)

< 400

352

110.93 ± 5.14

0.000

≥400

307

182.10 ± 8.41

Liver Cirrhosis

Absent

367

151.42 ± 7.10

0.099

Present

292

134.86 ± 6.80

HBV infection

Absent

178

139.84 ± 8.81

0.605

Present

481

145.65 ± 6.00

Tumor size

≥5 cm

483

168.09 ± 6.21

0.000

2–4.99 cm

146

78.72 ± 5.40

< 2 cm

30

75.69 ± 11.37

Tumor number

Single

363

124.66 ± 5.63

0.000

Multiple

296

167.92 ± 8.48

PVTT

Absent

417

113.58 ± 5.21

0.000

Present

242

196.65 ± 9.24

EHM

Absent

542

127.49 ± 5.03

0.000

Present

117

220.97 ± 13.55

Child-Pugh class

A

466

121.40 ± 5.23

0.000

B

164

200.40 ± 11.49

C

29

190.14 ± 24.27

  1. BCLC Barcelona Clinical Liver Cancer; AFP alpha-fetoprotein; HBV hepatitis B virus; PVTT portal vein tumor thrombus; EHM extrahepatic metastasis