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Table 6 Associations between mammographic density at diagnosis and pathological complete response following neoadjuvant chemotherapy - premenopausal patients

From: Mammographic density is a potential predictive marker of pathological response after neoadjuvant chemotherapy in breast cancer

 

BI-RADSa

N

N of cases

OR (95% CI)

Model 1

a

4

2

(ref)

b

27

2

0.08 (0.01–0.91)

c

71

13

0.22 (0.03–1.74)

d

13

1

0.08 (0.00–1.41)

Model 2

a

4

2

(ref)

b

27

2

0.05 (0.00–0.74)

c

71

13

0.15 (0.01–1.52)

d

13

1

0.05 (0.00–1.49)

Model 3

a

4

2

(ref)

b

27

2

0.07 (0.00–1.38)

c

71

13

0.15 (0.01–1.67)

d

13

1

0.03 (0.00–0.76)

  1. Odds ratio (OR) for pathological complete response (pCR)
  2. Model 1: crude analysis
  3. Model 2: minimally adjusted (age, BMI, pregnancies) analysis
  4. Model 3: fully adjusted (model 2 + ER, PR, Ki67, HER2, and tumor size at diagnosis) analysis
  5. aThroughout the table BI-RADS breast composition is intended