Mammographic density is a potential predictive marker of pathological response after neoadjuvant chemotherapy in breast cancer

Table 5 Associations between mammographic density at diagnosis and pathological complete response following neoadjuvant chemotherapy - all patients

	B-IRADS^a	N	N of cases	OR (95% CI)
Model 1	a	11	4	(ref)
	b	92	22	0.55 (0.15–2.06)
	c	108	17	0.33 (0.09–1.24)
	d	17	1	0.11 (0.01–1.16)
Model 2	a	11	4	(ref)
	b	92	22	0.47 (0.12–1.89)
	c	108	17	0.33 (0.08–1.44)
	d	17	1	0.10 (0.01–1.13)
Model 3	a	11	4	(ref)
	b	92	22	0.32 (0.07–1.50)
	c	108	17	0.30 (0.06–1.45)
	d	17	1	0.06 (0.01–0.56)

Odds ratio (OR) for pathological complete response (pCR)
Model 1: crude analysis
Model 2: minimally adjusted (age, BMI, menopause, pregnancies, HRT) analysis
Model 3: fully adjusted (model 2 + ER, PR, Ki67, HER2, and tumor size at diagnosis) analysis
^aThroughout the table BI-RADS breast composition is intended

ISSN: 1471-2407