Table 2 Clinical characteristics of patients in GSE24551, GSE39582 and TCGA database
From: Downregulated SPINK4 is associated with poor survival in colorectal cancer
Datasets | Characteristics | Â | Values | Â |
|---|---|---|---|---|
GSE24551 dataset | TNM stage | II | 90 | (56.3) |
| Â | III | 70 | (43.8) | |
Microsatellite status | MSS, MSI-L | 126 | (78.8) | |
| Â | MSI-H | 21 | (13.1) | |
| Â | Missing | 13 | (8.1) | |
GSE39582 dataset | Gender | Male | 288 | (54.5) |
| Â | Female | 240 | (45.5) | |
Age (years) |  | 66.6 ± 13.4 |  | |
TNM stage | 0 | 4 | (0.8) | |
| Â | I | 32 | (6.1) | |
| Â | II | 246 | (46.6) | |
| Â | III | 188 | (35.6) | |
| Â | IV | 58 | (11.0) | |
BRAF status | WT | 431 | (81.6) | |
| Â | MT | 47 | (8.9) | |
| Â | Missing | 50 | (9.5) | |
KRAS status | WT | 305 | (57.8) | |
| Â | MT | 202 | (38.3) | |
| Â | Missing | 21 | (4.0) | |
TP53 status | WT | 148 | (28.0) | |
| Â | MT | 174 | (33.0) | |
| Â | Missing | 206 | (39.0) | |
MMR status | pMMR | 413 | (78.2) | |
| Â | dMMR | 69 | (13.1) | |
| Â | Missing | 46 | (8.7) | |
TCGA database | Gender | Male | 234 | (53.4) |
| Â | Female | 204 | (46.6) | |
Age (years) |  | 66.6 ± 13.0 |  | |
TNM stage | I | 73 | (16.7) | |
| Â | II | 194 | (44.3) | |
| Â | III | 99 | (22.6) | |
| Â | IV | 61 | (13.9) | |
| Â | Missing | 11 | (2.5) | |
Pretreatment CEA level | Â | Â | Â | |
(ng/ml) | 38.4 ± 201.3 |  |  | |
Histological type | Adenocarcinoma | 373 | (85.2) | |
| Â | Mucinous adenocarcinoma | 60 | (13.7) | |
| Â | Missing | 5 | (1.1) | |
Perineural invasion | No | 131 | (29.9) | |
| Â | Yes | 45 | (10.3) | |
| Â | Missing | 262 | (59.8) | |
Tumor deposits | No | 184 | (42.0) | |
| Â | Yes | 38 | (8.7) | |
| Â | Missing | 216 | (49.3) | |
KRAS status | WT | 24 | (5.5) | |
| Â | MT | 22 | (5.0) | |
| Â | Missing | 392 | (89.5) |