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Table 1 Correlations between SPINK4 expression and the clinicopathological features of patients with CRC in our own study cohort

From: Downregulated SPINK4 is associated with poor survival in colorectal cancer

 

Low expression

High expression

P value

Gender

0.405

 Male

28

(50.0)

15

(60.0)

 

 Female

28

(50.0)

10

(40.0)

 

Age (years)

63.3 ± 12.4

 

64.1 ± 12.1

 

0.809

BMI (kg/m2)

22.0 ± 3.4

 

23.9 ± 2.5

 

0.031

TNM stage

0.025

 I-II

23

(41.1)

17

(68.0)

 

 III-IV

33

(58.9)

8

(32.0)

 

Tumor size (cm)

5.0 ± 2.0

 

4.1 ± 1.6

 

0.075

Histological type

0.366

 Adenocarcinoma

53

(94.6)

22

(88.0)

 

 Mucinous adenocarcinoma

3

(5.4)

3

(12.0)

0.306

Pretreatment CEA level (ng/mL)

11.1 ± 22.1

 

11.4 ± 22.1

 

0.953

Pretreatment CA199 level (U/ml)

32.8 ± 75.3

 

17.5 ± 17.9

 

0.319

Perineural invasion

4

(7.1)

0

(0.0)

 

Venus invasion

8

(14.3)

3

(12.0)

1.000

Tumor location

0.874

 Left colon

5

(8.9)

3

(12.0)

 

 Right colon

19

(33.9)

9

(36.0)

 

 Rectum

32

(57.1)

13

(52.0)

 

Tumor grade

0.583

 Well to moderately differentiated

54

(96.4)

23

(92.0)

 

 Poorly differentiated

2

(3.6)

2

(8.0)

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