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Table 2 Patients characteristics

From: Androgen receptor and FOXA1 coexpression define a “luminal-AR” subtype of feline mammary carcinomas, spontaneous models of breast cancer

Parameters

Categories

N

%

Breed

European shorthair or longhair

154

85.6%

Other breeds

26

14.4%

Gender

Intact female

112

62.2%

Neutered female

68

37.8%

History of contraception

Yes

76

42.2%

No

18

10.0%

Unknown

86

47.8%

Previous benign mammary lesions

Yes

16

8.9%

No

164

91.1%

Parity

Nulliparous

15

8.3%

Multiparous

21

11.7%

Unknown

144

80.0%

Multicentricity

Multiple FMCs

26

14.4%

Single FMC

154

85.6%

Pathologic tumor size

pT <  20 mm

85

47.2%

pT ≥ 20 mm

95

52.8%

Pathologic nodal stage

pN+ (nodal metastasis)

101

56.1%

pN0 (no)

20

11.1%

pNX (unknown)

59

32.8%

Distant metastasis

M1 (yes)

8

4.4%

M0 (no)

64

35.6%

MX (unknown)

108

60.0%

WHO stage

Stage I

45

25.0%

Stage II

23

12.8%

Stage III

104

57.8%

Stage IV

8

4.4%

WHO Histological type

Cribriform

54

30.0%

Comedocarcinoma

50

27.8%

Solid

27

15.0%

Mucinous

15

8.3%

Tubulopapillary

12

6.7%

Tubular

9

5.0%

Papillary

7

3.9%

Adenosquamous

4

2.2%

Anaplastic

2

1.1%

Elston and Ellis histological grade

Grade I

10

5.5%

Grade II

82

45.6%

Grade III

88

48.9%

Lymphovascular invasion

LVI+

110

61.1%

LVI–

70

38.9%

Tumor-associated inflammation

Absent to mild

77

42.8%

Moderate to severe

103

57.2%

Estrogen Receptor (ERα)

ER+ (ER ≥ 10%)

49

27.2%

ER– (ER < 10%)

131

72.8%

Progesterone Receptor (PR)

PR+ (PR ≥ 10%)

13

7.2%

PR– (PR < 10%)

167

92.8%

HER2 Score

0

103

57.2%

1+

59

32.8%

2+

18

10.0%

3+

0

0

Ki-67

High Ki-67 (≥ 20%)

169

93.9%

Low Ki-67 (<  20%)

11

6.1%

CK14

CK14+ (≥ 15%)

132

73.3%

CK14– (<  15%)

48

26.7%

  1. WHO World Health Organization