Comprehensive gene expression analysis for exploring the association between glucose metabolism and differentiation of thyroid cancer

Table 3 Univariate and multivariate analysis of influence on the recurrence of PTC

Variables (The first group is the reference group)	Univariate analysis		Multivariate analysis
Variables (The first group is the reference group)	H.R. (95% C.I.)	p-value	H.R. (95% C.I.)	p-value
Age (Continuous variable)	1.01 (0.99–1.04)	0.351	1.01 (0.99–1.04)	0.265
Gender (Female vs. Male)	1.56 (0.71–3.45)	0.272	1.98 (0.83–4.71)	0.124
T-stage (T1 + T2 vs. ≥T3)	1.36 (0.63–2.95)	0.435	1.41 (0.61–3.21)	0.420
N-stage (N0 vs. ≥N1)	3.76 (1.40–10.09)	0.008	4.24 (1.50–11.96)	0.006
TDS (Continuous variable)	0.76 (0.55–1.06)	0.102	0.83 (0.58–1.18)	0.293
Glycolysis signature (Continuous variable)	1.50 (1.03–2.17)	0.033	1.98 (1.26–3.10)	0.003

PTC Papillary Thyroid Cancer; H.R Hazard Ratio; C.I Confidence Interval; TDS Tumor Differentiation Score

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