Fig. 1

Phytochemicals inhibit migration of TNBC cells. a A micropatterned circular gap within a layer of BT-549 TNBC cells before migration (left, A₁), after 24 h (middle, A₂), and after 48 h (right, A₂) of migration. Bar graph in (a) shows percent migration, i.e., 1-(A₂/A₁), of BT-549 cells for two different time points. Each bar represents the mean of 8 replicates and each error bar represents standard error from the mean. Scale bar in (a) is 1 mm. b Representative images of migration inhibition of BT-549 cells with fisetin and quercetin treatments compared to non-treated cells. Scale bar in (b) is 1 mm. Inhibition of migration of nine TNBC cell lines by (c) fisetin and (d) quercetin. Each bar represents the mean of 8 replicates and error bars are standard error from the mean. Concentrations shown on the x-axis are threshold concentrations of the compounds to maintain a viability of over 90% for each cell line