Gene | OS | Adjusted OS | PFS | Adjusted PFS | ||||
---|---|---|---|---|---|---|---|---|
HR (95%CI) | P | HR (95%CI) | P | HR (95%CI) | P | HR (95%CI) | P | |
POSTN | 1.16 (1.09, 1.22) | 4.56E-07 | 1.09 (1.02, 1.16) | 0.0137 | 1.14 (1.06, 1.22) | 0.0003 | 1.09 (1.01, 1.17) | 0.0349 |
LUM | 1.18 (1.12, 1.25) | 2.67E-09 | 1.10 (1.03, 1.18) | 0.0039 | 1.17 (1.10, 1.26) | 6.17E-06 | 1.12 (1.04, 1.21) | 0.0043 |
THBS2 | 1.22 (1.15, 1.30) | 3.59E-10 | 1.13 (1.05, 1.21) | 0.0008 | 1.21 (1.12, 1.29) | 2.77E-07 | 1.13 (1.05, 1.23) | 0.0023 |
COL3A1 | 1.18 (1.12, 1.25) | 1.46E-08 | 1.10 (1.03, 1.18) | 0.0053 | 1.20 (1.12, 1.29) | 2.05E-07 | 1.14 (1.05, 1.23) | 0.0010 |
COL5A1 | 1.20 (1.14, 1.27) | 6.31E-11 | 1.13 (1.05, 1.21) | 0.0005 | 1.17 (1.09, 1.25) | 8.38E-06 | 1.11 (1.03, 1.20) | 0.0091 |
COL5A2 | 1.20 (1.14, 1.27) | 3.15E-11 | 1.12 (1.04, 1.19) | 0.0015 | 1.18 (1.10, 1.27) | 1.70E-06 | 1.12 (1.03, 1.21) | 0.0047 |
FAP | 1.20 (1.14, 1.27) | 2.52E-11 | 1.13 (1.06, 1.21) | 0.0003 | 1.18 (1.10, 1.26) | 1.61E-06 | 1.13 (1.05, 1.22) | 0.0019 |
FBN1 | 1.19 (1.12, 1.25) | 2.93E-09 | 1.12 (1.05, 1.19) | 0.0010 | 1.13 (1.05, 1.23) | 1.71E-06 | 1.18 (1.10, 1.27) | 0.0013 |