Table 1 miRNAs differentially expressed in CRC and their function in embryonic stem cells (ESC)

hsa-miR-17-3p

Up

Tumor tissue

[91]

Pluripotency

Up

Serum

[92]

Up

Tumor tissue

[93]

Up

Tumor tissue

[34]

hsa-miR-18a-5p

Up

Plasma

[94]

Pluripotency

Up

Fixed tumor tissue

[95]

Up

Tumor tissue

[93]

Up

Tumor tissue

[34]

Up

Tumor tissue

[96]

hsa-miR-18b-5p

Up

Tumor tissue

[97]

Pluripotency

Up

Tumor tissue

[98]

hsa-miR-19a-3p

Up

Serum

[99]

Pluripotency

Up

Serum

[92]

Up

Tumor tissue

[98]

Up

Tumor tissue

[96]

hsa-miR-19b-3p

Up

Tumor tissue

[96]

Pluripotency

Up

Serum

[92]

hsa-miR-20a-5p

Up

Tumor tissue

[93]

Pluripotency

Up

Serum

[92]

Up

Fixed tumor tissue

[95]

Up

Tumor tissue

[96]

hsa-miR-20b-5p

Down

Tumor tissue

[100]

Pluripotency

Up

Tumor tissue

[34]

hsa-miR-21-5p

Up

Serum

[99]

Differentiation

Up

Tumor tissue

[34]

Up

Fixed tumor tissue

[95]

Up

Tumor tissue

[96]

Up

Tumor tissue

[101]

hsa-miR-22-3p

Down

Tumor tissue

[102]

Differentiation

Down

Tumor tissue

[103]

Up

Tumor tissue

[101]

hsa-miR-23a-3p

Up

Tumor tissue

[104]

Differentiation

Up

Tumor tissue

[105]

hsa-miR-24-3p

Up

Serum

[92]

Differentiation

Down

Plasma

[36]

hsa-miR-27a-3p

Up

Tumor tissue

[106]

Differentiation

Down

Tumor tissue

[107]

hsa-miR-29a-3p

Up

Tumor tissue

[96]

Differentiation

Up

Fixed tumor tissue

[95]

hsa-miR-29b

Down

Tumor tissue

[108]

Pluripotency

Up

Tumor tissue

[96]

hsa-miR-30a-5p

Down

Tumor tissue

[96]

Differentiation

Down

Tumor tissue

[100]

hsa-miR-92a-3p

Up

Tumor tissue

[93]

Pluripotency

Up

Plasma

[93]

Up

Tumor tissue

[34]

Up

Fixed tumor tissue

[95]

hsa-miR-101-3p

Down

Tumor tissue

[109]

Pluripotency

Down

Serum

[110]

Down

Tumor tissue

[111]

hsa-miR-106a-5p

Up

Tumor tissue

[93]

Pluripotency

Up

Tumor tissue

[34]

Up

Tumor tissue

[96]

hsa-miR-145-5p

Down

Tumor tissue

[112]

Differentiation

Down

Tumor tissue

[34]

Down

Tumor tissue

[96]

hsa-miR-181d-5p

Up

Tumor tissue

[105]

Differentiation

Up

Fixed tumor tissue

[113]

hsa-miR-222-3p

Up

Tumor tissue

[93]

Differentiation

Up

Plasma

[93]

hsa-miR-302a-3p

Down

CRC cell lines

[114]

Pluripotency

hsa-miR-302a-5p

Unknown

–

–

Pluripotency

hsa-miR-302b-3p

Unknown

–

–

Pluripotency

hsa-miR-302b-5p

Unknown

–

–

Pluripotency

hsa-miR-302c-3p

Down

Plasma

[115]

Pluripotency

hsa-miR-302d-3p

Unknown

–

–

Pluripotency

hsa-miR-363-3p

Down

Tumor tissue

[116]

Pluripotency

hsa-miR-371a-3p

Unknown

–

–

Pluripotency

hsa-miR-372-3p

Up

Fixed tumor tissue

[113]

Pluripotency

hsa-miR-373-3p

Up

Fixed tumor tissue

[113]

Pluripotency

Up

Fixed tumor tissue

[117]