Fig. 3From: Focused screening reveals functional effects of microRNAs differentially expressed in colorectal cancermiR-101 activates intrinsic apoptosis pathway in HCT116 cells. (a) Representative images of HCT116 cells transfected with miR-101-3p, control PMC or lethal siRNA siUBC and stained with Hoechst (blue) and for cleaved caspase 8 (green) or cleaved caspase 9 (red). (b) Quantification plots showing a statistically significant increase in the percentages of Caspase 9 positive cells following transfection with miR-101-3p as compared to PMC (P < 0.05, unpaired one-tailed non-parametric Mann-Whitney test; n = 3 replica wells, 9 sites/well)Back to article page