Table 2 The toxicities of the combined chemotherapy of temozolomide, irinotecan and recombinant human endostatin
Toxicity | Any Grade (%) | Grade 3 and 4 (%) |
|---|---|---|
Hematologic | 22 (73.3) | 12 (40.0) |
 Leukopenia | 22 (73.3) | 11 (36.7) |
 Neutropenia | 22 (73.3) | 9 (30.0) |
 Thrombocytopenia | 4 (13.3) | 3 (10.0) |
 Lymphocytopenia | 2 (6.7) | 0 (0) |
Nonhematologic | ||
 Nausea and vomiting | 8 (26.7) | 0 (0) |
 Decreased appetite | 6 (20.0) | 0 (0) |
 Diarrhea | 2 (6.7) | 0 (0) |
 Elavated aminotransferase | 5 (16.7) | 1 (3.3) |
 Dizziness | 2 (6.7) | 0 (0) |
 Palpitation | 2 (6.7) | 0 (0) |
 Fatigue | 1 (3.3) | 0 (0) |