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Fig. 3 | BMC Cancer

Fig. 3

From: TOPK promotes metastasis of esophageal squamous cell carcinoma by activating the Src/GSK3β/STAT3 signaling pathway via γ-catenin

Fig. 3

The TOPK inhibitor, HI-TOPK-032 attenuates migration and invasion of esophageal squamous cell carcinoma (ESCC) cells. The KYSE510 cell (a) was treated with 0,0.5,1,5 and 10 μM HI-TOPK-032, while KYSE30 cell (b) was treated at 0, 0.25, 0.5,1 and 1.5 μM HI-TOPK-032 for 0, 24, 48 h and the cell migration was analyzed by wound healing assay. The KYSE510 (c) and KYSE30 cells (d) were treated with different concentrations of HI-TOPK-032 and seeded in the upper transwell chamber. The number of migrated cell was counted in transwell migration assay

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BMC Cancer

ISSN: 1471-2407

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