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Fig. 1 | BMC Cancer

Fig. 1

From: TOPK promotes metastasis of esophageal squamous cell carcinoma by activating the Src/GSK3β/STAT3 signaling pathway via γ-catenin

Fig. 1

TOPK was positively correlated with lymph node metastasis in patients with esophageal squamous cell carcinoma (ESCC). a) The immunohistochemical (IHC) staining of TOPK in ESCC tissues exhibiting lymph node metastasis. TOPK expression in N0 (n = 10) (left panel), N1–2 (n = 19) (middle panel), and N3 ESCC tissues (n = 18) (right panel). Scale bar: 200 μm (upper) and 50 μm (down). b) The IHC staining analysis of TOPK expression in the N0, N1–2, and N3 ESCC tissues. c) Western blotting analysis of TOPK expression in different ESCC cell lines. d Relative expression of TOPK in different ESCC cell lines compared to the TE1 cell line. **p < 0.01, ***p < 0.001 vs N0 group

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