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Table 3 Relative risk of second primary cancer by type of first primary cancer and follow-up period

From: The relative risk of second primary cancers in Switzerland: a population-based retrospective cohort study

 

6 months to 1 year

1 year to 5 years

5 years to 10 years

Over 10 years

First primary cancer

O

E

SIR

95%CI

O

E

SIR

95%CI

O

E

SIR

95%CI

O

E

SIR

95%CI

Oral Cavity & Pharynx

166

51

3.28

(2.75–3.80)

971

274

3.54

(3.31–3.77)

636

200

3.18

(2.93–3.44)

398

154

2.59

(2.33–2.86)

Oesophagus

30

17

1.78

(1.06–2.49)

131

52

2.51

(2.06–2.97)

47

24

1.97

(1.35–2.59)

36

13

2.82

(1.79–3.84)

Stomach

46

47

0.98

(0.67–1.30)

205

188

1.09

(0.93–1.25)

163

122

1.34

(1.12–1.55)

157

106

1.48

(1.24–1.73)

Colorectal

280

260

1.08

(0.95–1.21)

1671

1523

1.10

(1.04–1.15)

1332

1118

1.19

(1.13–1.26)

1158

900

1.29

(1.21–1.36)

Liver & Intrahepatic Bile Ducts

20

16

1.26

(0.62–1.89)

58

49

1.19

(0.85–1.52)

28

16

1.77

(1.03–2.52)

17

5

3.13

(1.40–4.87)

Pancreas

18

21

0.87

(0.40–1.33)

45

39

1.15

(0.78–1.52)

16

12

1.30

(0.56–2.05)

13

7

1.86

(0.66–3.06)

Larynx

53

20

2.61

(1.84–3.37)

361

130

2.77

(2.47–3.06)

256

110

2.34

(2.04–2.63)

223

102

2.19

(1.89–2.50)

Lung

201

136

1.47

(1.26–1.69)

642

420

1.53

(1.41–1.65)

411

214

1.92

(1.73–2.11)

306

143

2.15

(1.90–2.40)

Skin Melanoma

113

89

1.28

(1.03–1.52)

709

631

1.12

(1.04–1.21)

687

561

1.22

(1.13–1.32)

767

583

1.32

(1.22–1.41)

Breast female

197

252

0.78

(0.67–0.90)

1532

1807

0.85

(0.80–0.89)

1632

1617

1.01

(0.96–1.06)

1784

1570

1.14

(1.08–1.19)

Cervix Uteri

16

12

1.31

(0.56–2.06)

108

75

1.45

(1.16–1.74)

124

73

1.69

(1.38–2.01)

210

125

1.68

(1.44–1.92)

Corpus Uteri & NOS

46

49

0.95

(0.65–1.25)

386

335

1.15

(1.03–1.27)

359

320

1.12

(1.00–1.24)

530

386

1.37

(1.25–1.49)

Ovary

20

23

0.86

(0.43–1.30)

105

113

0.93

(0.74–1.12)

102

75

1.36

(1.08–1.65)

140

80

1.75

(1.44–2.05)

Prostate

348

509

0.68

(0.61–0.76)

2423

3409

0.71

(0.68–0.74)

1868

2461

0.76

(0.72–0.79)

999

1098

0.91

(0.85–0.97)

Testis

7

5

1.55

(0.10–3.00)

63

39

1.60

(1.17–2.03)

70

53

1.33

(0.99–1.67)

207

152

1.36

(1.17–1.56)

Kidney

65

40

1.64

(1.21–2.07)

318

251

1.27

(1.12–1.41)

243

198

1.23

(1.07–1.39)

240

164

1.47

(1.27–1.66)

Bladder

150

85

1.77

(1.47–2.06)

679

476

1.43

(1.32–1.54)

483

338

1.43

(1.30–1.56)

431

266

1.62

(1.46–1.78)

Brain & Central Nerves

15

10

1.52

(0.62–2.43)

38

30

1.27

(0.82–1.72)

25

20

1.26

(0.70–1.82)

35

19

1.83

(1.15–2.50)

Thyroid

20

14

1.46

(0.73–2.20)

151

103

1.46

(1.22–1.71)

125

104

1.20

(0.98–1.42)

205

131

1.57

(1.34–1.80)

Hodgkin Lymphoma

8

5

1.53

(0.21–2.85)

99

34

2.89

(2.28–3.49)

70

33

2.09

(1.56–2.62)

146

52

2.78

(2.30–3.26)

Non Hodgkin Lymphoma

81

64

1.26

(0.97–1.56)

494

388

1.27

(1.16–1.39)

401

286

1.40

(1.26–1.54)

347

215

1.62

(1.44–1.79)

Multiple Myeloma

21

28

0.75

(0.38–1.12)

145

140

1.04

(0.86–1.21)

91

63

1.44

(1.13–1.76)

36

26

1.38

(0.88–1.88)

Leukaemia

51

45

1.14

(0.80–1.48)

971

266

1.43

(1.29–1.58)

308

183

1.68

(1.49–1.88)

218

119

1.83

(1.57–2.08)

All Cancers

2098

1901

1.10

(1.06–1.15)

12,532

11,297

1.11

(1.09–1.13)

10,011

8556

1.17

(1.15–1.19)

9152

6706

1.36

(1.34–1.39)

  1. O: number of observed cases
  2. E: number of expected cases
  3. SIR: standardized incidence ratio
  4. 95%CI: 95% confidence intervals