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Table 2 Comparison of clinical characteristics between patients with and without a cough

From: A cross sectional study to determine the prevalence of cough and its impact in patients with lung cancer: a patient unmet need

CharacteristicSubgroupCough, N (%)No Cough, N (%)p-value
Mean age in years (SD) 67 years (9.02)66 years (8.85)0.56
Male sex 57 (50)49 (56)0.34
Smoking statusNever smoked12 (10)7 (8)0.44
Former73 (64)62 (72)
Current30 (26)17 (20)
Median no. pack years on ever smokers (25th–75th IQR) 38 (17.5–46)33 (17.5–50)1.00
Performance status015 (13)12 (14)0.09
133 (29)39 (45)
246 (40)25 (29)
321 (18)11 (12)
StageEarly NSCLC (incl IIIA)14 (12)12 (14)0.61
Advanced NSCLC63 (56)47 (55)
Limited stage SCLC12 (11)5 (6)
Extensive stage SCLC24 (21)22 (25)
HistologyNon-small cell lung cancer76 (67)59 (68)1.00
Small cell lung cancer36 (31)27 (31)
Mixed2 (2)1 (1)
Non-small cell lung cancer histological subtypeAdenocarcinoma44 (55)40 (65)0.29
Squamous25 (31)16 (26)
Not otherwise specified10 (13)3 (5)
Mixed1 (1)1 (2)
Large cell0 (0)1 (2)
On anticancer therapyYes45 (40)47 (54)0.04
What type of anticancer therapyChemotherapy28 (62)30 (65)0.44
Radiotherapy3 (7)0 (0)
Concurrent2 (4)2 (4)
Tyrosine-kinase inhibitors12 (27)14 (31)
If not on anticancer therapy, why notPre-treatment16 (23)13 (31)0.33
Post palliative treatment24 (34)18 (43)
Post curative treatment6 (9)3 (7)
No further treatment24 (34)8 (19)
ComorbiditiesNausea42 (36)33 (38)0.79
Gastro-oesophageal reflux62 (54)44 (51)0.70
  1. NSCLC Non-small cell lung cancer, SCLC: Small cell lung cancer