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Table 3 Summary of all criteria as proposed by us for the definition of the oligometastatic disease in pancreatic cancer

From: Proposal for a definition of "Oligometastatic disease in pancreatic cancer"

Criteria for Oligometastatic Disease in Pancreatic Ductal Adenocarcinoma
 InclusionExclusion
ECOG0/1>/= 2
Liver/lung only (+LN hepatoduodenal lig.)YesNo
Number of hepatic or pulmonary lesions</= 4>  4
AscitesNoYes
Liver cirrhosisNoYes
Lung emphysemaNoYes
CA 19–9 (U/mL)a<  1000>  1000
Surgery for metastasisbAtypical resection (+/−Ablation)Non-resectable/major hepatic/lung surgery necessary
Primary tumor upon diagnosisbResectable, borderline resectable, non-resectablec 
Chemotherapy responseResponse or stable diseaseProgressive disease
  1. aHartwig et al. 2013 Ann Surg Oncol (2013) 20:2188–2196; DOI 10.1245/s10434-012-2809-1: R0 Resection rate CA 19-9 > 1000U/ml as low as 15%
  2. bResectability of primary tumor and expected extension of hepatic resection to be evaluated by experienced HPB surgeon together with a radiologist
  3. cAs defined in: Isaji, S. et al. International consensus on definition and criteria of borderline resectable pancreatic ductal adenocarcinoma 2017. Pancreatology 18, (2018)