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Table 4 Interaction of FB1 and AFB1 exposure on risk of esophageal cancer

From: Mycotoxin exposure is associated with increased risk of esophageal squamous cell carcinoma in Huaian area, China

FB1 exposurea

AFB1 exposureb

Cases (%)

Controls (%)

p

OR (95% CI)

Low

Low

14 (7.36)

100 (26.32)

 

1

High

Low

50 (26.32)

88 (23.16)

< 0.001

4.057 (2.101, 7.834)

Low

High

25 (13.16)

90 (23.68)

0.060

1.983 (0.972, 4.048)

High

High

101 (53.16)

102 (26.84)

< 0.001

7.070 (3.791, 13.187)

Relative excess risk due to interaction (RERI)

   

2.030 (−0.591, 4.651)

Proportion attributable to interaction (AP)

   

0.287 (−0.029, 0.603)

Synergy index (S)

   

1.502 (0.864, 2.612)

  1. Exposure levels are indicated by levels of urinary FB1a and serum AFB1-lysineb