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Table 2 Univariate Cox regression model analysis for overall survival and cancer specific survival in nomogram cohort

From: Nomograms to predict individual prognosis of patients with squamous cell carcinoma of the urinary bladder

Characteristics Overall Survival (OS) Cancer Specific Survival (CSS)
HRa (95% CIb) P-value HR (95% CI) P-value
Age at diagnosis
 < 50 1 (Reference)   1 (Reference)  
 50–59 0.842 (0.632–1.121) 0.239 0.782 (0.581–1.053) 0.105
 60–69 0.861 (0.654–1.134) 0.288 0.746 (0.560–0.995) 0.046
 70–79 1.040 (0.803–1.349) 0.765 0.876 (0.668–1.149) 0.338
 80–89 1.655 (1.276–2.146) < 0.001 1.313 (1.000–1.725) 0.050
 90–100 2.447 (1.701–3.520) < 0.001 1.983 (1.341–2.931) 0.001
Marital status
 Married 1 (Reference)   1 (Reference)  
 Single 1.756 (1.528–2.017) < 0.001 1.761 (1.511–2.052) < 0.001
 Unknown 1.614 (1.163–2.240) 0.004 1.610 (1.122–2.312) 0.010
Race
 Black 1 (Reference)   1 (Reference)  
 White 0.827 (0.678–1.008) 0.060 0.809 (0.651–1.005) 0.055
 Other 0.624 (0.423–0.920) 0.017 0.696 (0.464–1.044) 0.079
Sex
 Female 1 (Reference)   1 (Reference)  
 Male 0.773 (0.677–0.883) < 0.001 0.746 (0.644–0.864) < 0.001
Grade
 I 1 (Reference)   1 (Reference)  
 II 0.943 (0.772–1.151) 0.564 0.903 (0.727–1.121) 0.354
 III 0.825 (0.700–0.972) 0.021 0.855 (0.715–1.023) 0.086
 IV 0.867 (0.769–0.976) 0.019 0.905 (0.794–1.032) 0.135
T
 T1 1 (Reference)   1(Reference)  
 T2 0.939 (0.760–1.161) 0.562 0.947 (0.746–1.201) 0.652
 T3 0.634 (0.501–0.802) < 0.001 0.656 (0.504–0.853) 0.002
 T4 1.473 (1.175–1.846) 0.001 1.598 (1.246–2.050) < 0.001
 Ta 0.492 (0.181–1.334) 0.163 0.486 (0.154–1.537) 0.220
 Tis 0.928 (0.453–1.902) 0.839 0.576 (0.212–1.570) 0.281
N
 N0 1 (Reference)   1 (Reference)  
 N1 1.654 (1.332–2.054) < 0.001 1.810 (1.439–2.277) < 0.001
 N2 1.707 (1.352–2.154) < 0.001 1.933 (1.514–2.466) < 0.001
 N3 2.608 (0.837–8.122) 0.098 3.189 (1.023–9.941) 0.046
M
 M0 1 (Reference)   1 (Reference)  
 M1 3.071 (2.509–3.758) < 0.001 3.439 (2.786–4.246) < 0.001
RCc
 No 1 (Reference)   1 (Reference)  
 Yes 0.400 (0.347–0.462) < 0.001 0.389 (0.332–0.456) < 0.001
Metastasectomy
 No 1 (Reference)   1 (Reference)  
 Yes 1.009 (0.775–1.315) 0.944 0.991 (0.739–1.328) 0.950
Radiation
 No/unknown 1 (Reference)   1 (Reference)  
 Yes 1.116 (0.946–1.316) 0.192 1.132 (0.946–1.355) 0.175
Chemotherapy
 No/unknown 1 (Reference)   1 (Reference)  
 Yes 0.824 (0.709–0.956) 0.011 0.870 (0.740–1.023) 0.092
Size
 ≤ 6.5 cm 1 (Reference)   1 (Reference)  
 >6.5 cm 1.736 (1.459–2.065) < 0.001 1.806 (1.492–2.187) < 0.001
 Unknown 2.119 (1.815–2.474) < 0.001 2.151 (1.812–2.555) < 0.001
LNRd
 0 1 (Reference)   1(Reference)  
 ≤ 0.0385 1.796 (0.842–3.830) 0.130 1.730 (0.706–4.240) 0.230
 >0.0385 3.307 (2.562–4.269) < 0.001 4.164 (3.145–5.514) < 0.001
 Unknown 3.293(2.761–3.927) < 0.001 3.805 (3.098–4.674) < 0.001
  1. aHR Hazard ratio
  2. bCI Confidence interval
  3. cRC Radical cystectomy
  4. dLNR Lymph node ratio