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Table 2 Univariate Cox regression model analysis for overall survival and cancer specific survival in nomogram cohort

From: Nomograms to predict individual prognosis of patients with squamous cell carcinoma of the urinary bladder

Characteristics

Overall Survival (OS)

Cancer Specific Survival (CSS)

HRa (95% CIb)

P-value

HR (95% CI)

P-value

Age at diagnosis

 < 50

1 (Reference)

 

1 (Reference)

 

 50–59

0.842 (0.632–1.121)

0.239

0.782 (0.581–1.053)

0.105

 60–69

0.861 (0.654–1.134)

0.288

0.746 (0.560–0.995)

0.046

 70–79

1.040 (0.803–1.349)

0.765

0.876 (0.668–1.149)

0.338

 80–89

1.655 (1.276–2.146)

< 0.001

1.313 (1.000–1.725)

0.050

 90–100

2.447 (1.701–3.520)

< 0.001

1.983 (1.341–2.931)

0.001

Marital status

 Married

1 (Reference)

 

1 (Reference)

 

 Single

1.756 (1.528–2.017)

< 0.001

1.761 (1.511–2.052)

< 0.001

 Unknown

1.614 (1.163–2.240)

0.004

1.610 (1.122–2.312)

0.010

Race

 Black

1 (Reference)

 

1 (Reference)

 

 White

0.827 (0.678–1.008)

0.060

0.809 (0.651–1.005)

0.055

 Other

0.624 (0.423–0.920)

0.017

0.696 (0.464–1.044)

0.079

Sex

 Female

1 (Reference)

 

1 (Reference)

 

 Male

0.773 (0.677–0.883)

< 0.001

0.746 (0.644–0.864)

< 0.001

Grade

 I

1 (Reference)

 

1 (Reference)

 

 II

0.943 (0.772–1.151)

0.564

0.903 (0.727–1.121)

0.354

 III

0.825 (0.700–0.972)

0.021

0.855 (0.715–1.023)

0.086

 IV

0.867 (0.769–0.976)

0.019

0.905 (0.794–1.032)

0.135

T

 T1

1 (Reference)

 

1(Reference)

 

 T2

0.939 (0.760–1.161)

0.562

0.947 (0.746–1.201)

0.652

 T3

0.634 (0.501–0.802)

< 0.001

0.656 (0.504–0.853)

0.002

 T4

1.473 (1.175–1.846)

0.001

1.598 (1.246–2.050)

< 0.001

 Ta

0.492 (0.181–1.334)

0.163

0.486 (0.154–1.537)

0.220

 Tis

0.928 (0.453–1.902)

0.839

0.576 (0.212–1.570)

0.281

N

 N0

1 (Reference)

 

1 (Reference)

 

 N1

1.654 (1.332–2.054)

< 0.001

1.810 (1.439–2.277)

< 0.001

 N2

1.707 (1.352–2.154)

< 0.001

1.933 (1.514–2.466)

< 0.001

 N3

2.608 (0.837–8.122)

0.098

3.189 (1.023–9.941)

0.046

M

 M0

1 (Reference)

 

1 (Reference)

 

 M1

3.071 (2.509–3.758)

< 0.001

3.439 (2.786–4.246)

< 0.001

RCc

 No

1 (Reference)

 

1 (Reference)

 

 Yes

0.400 (0.347–0.462)

< 0.001

0.389 (0.332–0.456)

< 0.001

Metastasectomy

 No

1 (Reference)

 

1 (Reference)

 

 Yes

1.009 (0.775–1.315)

0.944

0.991 (0.739–1.328)

0.950

Radiation

 No/unknown

1 (Reference)

 

1 (Reference)

 

 Yes

1.116 (0.946–1.316)

0.192

1.132 (0.946–1.355)

0.175

Chemotherapy

 No/unknown

1 (Reference)

 

1 (Reference)

 

 Yes

0.824 (0.709–0.956)

0.011

0.870 (0.740–1.023)

0.092

Size

 ≤ 6.5 cm

1 (Reference)

 

1 (Reference)

 

 >6.5 cm

1.736 (1.459–2.065)

< 0.001

1.806 (1.492–2.187)

< 0.001

 Unknown

2.119 (1.815–2.474)

< 0.001

2.151 (1.812–2.555)

< 0.001

LNRd

 0

1 (Reference)

 

1(Reference)

 

 ≤ 0.0385

1.796 (0.842–3.830)

0.130

1.730 (0.706–4.240)

0.230

 >0.0385

3.307 (2.562–4.269)

< 0.001

4.164 (3.145–5.514)

< 0.001

 Unknown

3.293(2.761–3.927)

< 0.001

3.805 (3.098–4.674)

< 0.001

  1. aHR Hazard ratio
  2. bCI Confidence interval
  3. cRC Radical cystectomy
  4. dLNR Lymph node ratio