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Table 2 Univariate Cox regression model analysis for overall survival and cancer specific survival in nomogram cohort

From: Nomograms to predict individual prognosis of patients with squamous cell carcinoma of the urinary bladder

CharacteristicsOverall Survival (OS)Cancer Specific Survival (CSS)
HRa (95% CIb)P-valueHR (95% CI)P-value
Age at diagnosis
 < 501 (Reference) 1 (Reference) 
 50–590.842 (0.632–1.121)0.2390.782 (0.581–1.053)0.105
 60–690.861 (0.654–1.134)0.2880.746 (0.560–0.995)0.046
 70–791.040 (0.803–1.349)0.7650.876 (0.668–1.149)0.338
 80–891.655 (1.276–2.146)< 0.0011.313 (1.000–1.725)0.050
 90–1002.447 (1.701–3.520)< 0.0011.983 (1.341–2.931)0.001
Marital status
 Married1 (Reference) 1 (Reference) 
 Single1.756 (1.528–2.017)< 0.0011.761 (1.511–2.052)< 0.001
 Unknown1.614 (1.163–2.240)0.0041.610 (1.122–2.312)0.010
Race
 Black1 (Reference) 1 (Reference) 
 White0.827 (0.678–1.008)0.0600.809 (0.651–1.005)0.055
 Other0.624 (0.423–0.920)0.0170.696 (0.464–1.044)0.079
Sex
 Female1 (Reference) 1 (Reference) 
 Male0.773 (0.677–0.883)< 0.0010.746 (0.644–0.864)< 0.001
Grade
 I1 (Reference) 1 (Reference) 
 II0.943 (0.772–1.151)0.5640.903 (0.727–1.121)0.354
 III0.825 (0.700–0.972)0.0210.855 (0.715–1.023)0.086
 IV0.867 (0.769–0.976)0.0190.905 (0.794–1.032)0.135
T
 T11 (Reference) 1(Reference) 
 T20.939 (0.760–1.161)0.5620.947 (0.746–1.201)0.652
 T30.634 (0.501–0.802)< 0.0010.656 (0.504–0.853)0.002
 T41.473 (1.175–1.846)0.0011.598 (1.246–2.050)< 0.001
 Ta0.492 (0.181–1.334)0.1630.486 (0.154–1.537)0.220
 Tis0.928 (0.453–1.902)0.8390.576 (0.212–1.570)0.281
N
 N01 (Reference) 1 (Reference) 
 N11.654 (1.332–2.054)< 0.0011.810 (1.439–2.277)< 0.001
 N21.707 (1.352–2.154)< 0.0011.933 (1.514–2.466)< 0.001
 N32.608 (0.837–8.122)0.0983.189 (1.023–9.941)0.046
M
 M01 (Reference) 1 (Reference) 
 M13.071 (2.509–3.758)< 0.0013.439 (2.786–4.246)< 0.001
RCc
 No1 (Reference) 1 (Reference) 
 Yes0.400 (0.347–0.462)< 0.0010.389 (0.332–0.456)< 0.001
Metastasectomy
 No1 (Reference) 1 (Reference) 
 Yes1.009 (0.775–1.315)0.9440.991 (0.739–1.328)0.950
Radiation
 No/unknown1 (Reference) 1 (Reference) 
 Yes1.116 (0.946–1.316)0.1921.132 (0.946–1.355)0.175
Chemotherapy
 No/unknown1 (Reference) 1 (Reference) 
 Yes0.824 (0.709–0.956)0.0110.870 (0.740–1.023)0.092
Size
 ≤ 6.5 cm1 (Reference) 1 (Reference) 
 >6.5 cm1.736 (1.459–2.065)< 0.0011.806 (1.492–2.187)< 0.001
 Unknown2.119 (1.815–2.474)< 0.0012.151 (1.812–2.555)< 0.001
LNRd
 01 (Reference) 1(Reference) 
 ≤ 0.03851.796 (0.842–3.830)0.1301.730 (0.706–4.240)0.230
 >0.03853.307 (2.562–4.269)< 0.0014.164 (3.145–5.514)< 0.001
 Unknown3.293(2.761–3.927)< 0.0013.805 (3.098–4.674)< 0.001
  1. aHR Hazard ratio
  2. bCI Confidence interval
  3. cRC Radical cystectomy
  4. dLNR Lymph node ratio