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Table 5 The results of the meta-analysis for the effect of propofol and sevoflurane on postoperative cognitive function

From: A systematic review: comparative analysis of the effects of propofol and sevoflurane on postoperative cognitive function in elderly patients with lung cancer

Comparative items

Data type

Heterogeneity test

Test of Association

Publication bias

MMSE and protein marker

Items

Q value

d.f.

I-squared

Tau-squared

P Value

Heterogeneity

Effect model

Pooled WMD

WMD 95% CI

Pooled SMD

SMD

95% CI

Z value

P value

Statistical significance

Preoperative cognitive function

Preoperative MMSE

Continuous

55.09

12

78.2%

0.1449

0.000

Yes

Random

-0.040

[−0.288, 0.208]

− 0.038

[− 0.274, 0.198]

0.31

0.753

No

No

Postoperative cognitive function evaluation

MMSE 6 h

Continuous

199.17

10

95.0%

1.0826

0.000

Yes

Random

−1.922

[−2.571, − 1.274]

−1.391

[− 2.024, −0.757]

4.30

0.000

Yes

No

MMSE 24 h

Continuous

216.54

13

94.0%

0.7859

0.000

Yes

Random

−1.504

[−2.253, −0.755]

− 1.106

[− 1.588, − 0.624]

4.50

0.000

Yes

No

MMSE 3d

Continuous

140.36

10

92.9%

0.6585

0.000

Yes

Random

−1.376

[−2.044, −0.708]

− 1.065

[− 1.564, − 0.566]

4.19

0.000

Yes

No

MMSE 7d

Continuous

16.75

9

46.3%

NA

0.053

No

fixed

−0.371

[−0.493, − 0.249]

−0.422

[− 0.549, − 0.295]

6.52

0.000

Yes

No

Protein marker S100β

S100β 1d

Continuous

67.94

12

82.3%

0.2024

0.000

Yes

Random

0.018

[0.016, 0.020]

0.746

[0.475, 1.017]

5.39

0.000

Yes

No