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Fig. 4 | BMC Cancer

Fig. 4

From: Loss of the SWI/SNF-ATPase subunit members SMARCF1 (ARID1A), SMARCA2 (BRM), SMARCA4 (BRG1) and SMARCB1 (INI1) in oesophageal adenocarcinoma

Fig. 4

Loss of ARID1a in TP53 loss, microsatellite-stable (MSS) EAC. (a + b) EAC of the gastroesophageal junction (arrow highlights gastric mucosa; HE, × 5) with (c) loss of ARID1a (IHC, × 10), (d) strong nuclear positivity of TP53 as a sign of TP53 loss (IHC, × 10) and (e) nuclear positivity of the mismatch-repair-proteins MSH6 (IHC, × 10) and (f) MLH1 (IHC, × 10)

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