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Table 2 Comparison of the clinical characteristics of good responders and poor responderss

From: Predicting prognosis according to preoperative chemotherapy response in patients with locally advanced lower rectal cancer

 

Total

(N = 102)

Good responders

(N = 47)

Poor responders

(N = 55)

p

Sex, N (%)

 Male

69 (67.6)

28 (59.6)

41 (74.5)

0.11

 Female

33 (32.4)

19 (40.4)

14 (25.5)

 

Age (years), N (%)

  < 65

80 (78.4)

35 (74.5)

45 (81.8)

0.37

  ≥ 65

22 (21.6)

12 (25.5)

10 (18.2)

 

AV distance (cm), N (%)

  < 5

62 (60.8)

32 (68.1)

30 (54.5)

0.16

  ≥ 5

40 (39.2)

15 (31.9)

25 (45.5)

 

CEA level (ng/mL), N (%)

  < 5

69 (67.6)

30 (63.8)

39 (70.9)

0.45

  ≥ 5

33 (32.4)

17 (36.2)

16 (29.1)

 

cT stage, N (%)

 T2

2 (2.0)

1 (2.1)

1 (1.8)

0.17

 T3

77 (75.5)

38 (80.9)

39 (70.9)

 

 T4

23 (22.5)

8 (17.0)

15 (27.3)

 

cN stage, N (%)

 Negative

52 (51.0)

26 (55.3)

26 (47.3)

0.42

 Positive

50 (49.0)

21 (44.7)

29 (52.7)

 

Clinical LPLN metastasis, N (%)

 Negative

78 (76.5)

37 (78.7)

41 (74.5)

0.62

 Positive

24 (23.5)

10 (21.3)

14 (25.5)

 

Clinical CRM, N (%)

 Negative

73 (71.6)

34 (72.3)

39 (70.9)

0.87

 Positive

29 (28.4)

13 (27.7)

16 (29.1)

 

mrEMVI, N (%)

 Negative

78 (76.5)

38 (80.9)

40 (72.7)

0.34

 Positive

24 (23.5)

9 (19.1)

15 (27.3)

 

ymrEMVI, N (%)

 Negative

80 (78.4)

39 (83.0)

41 (74.5)

0.30

 Positive

22 (21.6)

8 (17.0)

14 (25.5)

 
  1. AV anal verge, CEA carcinoembryonic antigen, LPLN lateral pelvic lymph node, CRM circumferential resection margin, mrEMVI extramural venous invasion based on magnetic resonance imaging before neoadjuvant chemotherapy, ymrEMVI extramural venous invasion based on magnetic resonance imaging after neoadjuvant chemotherapy