Fig. 3

Hazard ratio (95% confidence interval) and Kaplan Meier curves for the association of acylcarnitines with PSA progression. a Hazard ratios and 95% confidence interval (CI) for the association of the complete panel of acylcarnitines with the risk of PSA progression. Groups (lower and higher risk) were separate by median cut-off (suffix “_med”) of the normalized abundances for each molecule. C4 = butyrylcarnitine, C4_M = methylmalonylcarnitine. b PSA progression-free survival calculated by the Kaplan Meier method for acetylcarnitine (C2). Groups are defined by median-cut off of normalized abundances (vs L-carnitine) of high acetylcarnitine (C2 High, blue solid line) vs low acetylcarnitne (C2 Low, red dotted line). P-value was estimated with Log-Rank test. c PSA progression free survival calculated by the Kaplan Meier method for isovalerylcarnitine (C5). Groups are defined by median-cut off of normalized abundances (versus L-carnitine) of High isovalerylcarnitine (C5 High, red dot line) versus low isovelrylcarnitne (C5 Low, blue solid line). P-value was estimated with Log-Rank test. d PSA progression-free survival calculated by the Kaplan Meier method for hexanoylcarnitine (C6). Groups are defined by median-cut off of normalized abundances (vs L-carnitine) of high hexanoylcarnitine (C6 High, blue solid line) versus low hexanoylcarnitne (C6 Low, red dotted line). P-value was estimated with Log-Rank test. For statistical details see Methods section