Skip to main content

Table 3 Extensive evaluations of associations between the clinicopathological variables and the UGT2B28-rs2132039 variant types (i.e. the dependent variable, TT = 0, Non-TT = 1) using univariate and multivariate logistic regression analysis

From: Ages of hepatocellular carcinoma occurrence and life expectancy are associated with a UGT2B28 genomic variation

CharacteristicOdds ratio95%CIP-value
Univariate analysis
 Gender, male0.8240.509–1.3340.431
 Age at diagnosis, years1.0211.006–1.0360.005*
 Tumor size, cm0.9810.932–1.0320.449
 Tumor number1.0840.886–1.3280.432
 Capsule1.0940.695–1.7210.699
 Tumor grade0.9400.698–1.2660.685
 Macrovascular invasion0.8420.440–1.6100.603
 Microvascular invasion0.7600.493–1.1700.212
 Cirrhosis1.0720.713–1.6130.737
 Ascites3.2231.264–8.2150.014*
 Alcoholism0.8450.533–1.3400.475
 HBV0.7100.458–1.1010.126
 HCV1.8391.148–2.9450.011*
 HBV + HCV1.2910.644–2.5880.471
 NBNC0.8480.479–1.5020.572
 Prothrombin time, second0.9380.811–1.0840.385
 AST, U/L1.0020.999–1.0050.246
 ALT, U/L1.0031.000–1.0050.095
 Bilirubin, mg/dL0.9600.808–1.1420.646
 Albumin, g/dL0.8200.572–1.1750.279
 Creatinine, mg/dL0.9760.790–1.2060.823
 Alpha-fetoprotein, ng/mL1.0001.000–1.0000.377
 Recurrent1.2080.806–1.8110.359
 Recurrent time, month0.9950.988–1.0010.113
 Metastasis0.6920.415–1.1560.160
 Metastatic time, month0.9980.991–1.0040.435
 Death0.7670.416–1.4140.395
 Survival time, month0.9980.992–1.0050.632
Multivariate analysis
 Age, years1.0161.001–1.0320.037*
 Ascites3.5051.358–9.0480.010*
 HCV1.6460.999–2.7130.050
  1. Abbreviations: CI Confidence interval, HBV Hepatitis B virus carrier, HCV Hepatitis C virus carrier, HBV + HCV Co-infection of hepatitis B virus and hepatitis C virus, NBNC Non-hepatitis B/hepatitis C virus carrier, AST Aspartate aminotransferase, ALT Alanine aminotransferase
  2. *P < 0.05 were indicated as bold face with an asterisk