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Table 5 Clinical outcome of adults with localized Ewing sarcoma

From: Impact of chemotherapy cycles and intervals on outcomes of nonspinal Ewing sarcoma in adults: a real-world experience

ReferencesStudy groupCT regimensOutcomes
Womer et al. [5]Prospective study
31 patients ≥18 y (2001–2005, USA)
VDC/IE (including every 2-week protocol)
14 cycles
5-y EFS 47%
Gupta et al. [23]Retrospective study
24 patients ≥18 y (1990–2005, Canada)
VDC/IE
10 cycles
3-y EFS 43%
3-y OS 59%
Seker et al. [22]Retrospective study
21 patients ≥19 y (2000–2012, Turkey)
VDC/IE
17 cycles
5-y OS 64%
The present studyRetrospective study
27 patients ≥18 y
(2005–2017, China)
VDC/IE
≥ 12 cycles
3-y EFS 60%
3-y OS 81%
5-y EFS 38%
5-y OS 51%
  1. CT Chemotherapy, VDC/IE Vincristine, doxorubicin, and cyclophosphamide alternating with ifosfamide and etoposide, EFS Event-free survival, OS Overall survival
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