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Table 5 Clinical outcome of adults with localized Ewing sarcoma

From: Impact of chemotherapy cycles and intervals on outcomes of nonspinal Ewing sarcoma in adults: a real-world experience

References

Study group

CT regimens

Outcomes

Womer et al. [5]

Prospective study

31 patients ≥18 y (2001–2005, USA)

VDC/IE (including every 2-week protocol)

14 cycles

5-y EFS 47%

Gupta et al. [23]

Retrospective study

24 patients ≥18 y (1990–2005, Canada)

VDC/IE

10 cycles

3-y EFS 43%

3-y OS 59%

Seker et al. [22]

Retrospective study

21 patients ≥19 y (2000–2012, Turkey)

VDC/IE

17 cycles

5-y OS 64%

The present study

Retrospective study

27 patients ≥18 y

(2005–2017, China)

VDC/IE

≥ 12 cycles

3-y EFS 60%

3-y OS 81%

5-y EFS 38%

5-y OS 51%

  1. CT Chemotherapy, VDC/IE Vincristine, doxorubicin, and cyclophosphamide alternating with ifosfamide and etoposide, EFS Event-free survival, OS Overall survival