Toxicity and grade | Number | Percentage |
---|---|---|
Hematological toxicities | ||
Neutropenia | ||
All | 81 | 100 |
3–4 | 77 | 95.1 |
Anemia | ||
All | 29 | 35.8 |
3–4 | 17 | 21.0 |
Thrombocytopenia | ||
All | 76 | 93.8 |
3–4 | 45 | 55.6 |
Nausea and vomiting | ||
All | 61 | 75.3 |
3–4 | 20 | 24.7 |
Hepatic dysfunction | ||
All | 13 | 16.0 |
3–4 | 6 | 7.4 |
Renal dysfunction | ||
1–2 | 4 | 4.9 |
Mucositis | ||
All | 16 | 19.8 |
3–4 | 9 | 11.1 |
Cardiac toxicities | ||
Arrhythmia | ||
1–2 | 11 | 13.6 |
Myocardial ischemia | ||
1–2 | 7 | 8.6 |
Hemorrhagic cystitis | ||
1–2 | 4 | 4.9 |
Neurologic toxicity | ||
All | 10 | 12.3 |
3–4 | 1 | 1.23 |
Dose reduction | ||
All | 48 | 59.3 |