Prognostic implications of forkhead box protein O1 (FOXO1) and paired box 3 (PAX3) in epithelial ovarian cancer

BMC Cancer

Table 1 Expressions of FOXO1 and PAX3 in relation to clinicopathological characteristics in IHC analysis

	No.	FOXO1		No.	PAX3
	No.	Mean score (95% CI)	p-value	No.	Mean score (95% CI)	p-value
All study subjects	310	110.9 [105.7–116.0]		310	125.2 [119.7–130.8]
Diagnostic category
Normal	57	85.3 [79.9–90.8]	< 0.001	70	93.6 [87.2–100.0]	< 0.001
Benign	42	90.3 [78.7–101.8]		31	95.2 [82.3–108.1]
Borderline	46	93.6 [85.4–101.9]		42	107.0 [96.1–117.8]
Cancer	165	129.8 [122.1–137.5]		167	148.7 [140.9–156.5]
FIGO stage			0.854			0.230
I-II	43	131.1 [115.2–147.0]		43	143.3 [130.8–155.8]
III-IV	106	132.8 [123.3–142.3]		107	154.1 [143.9–164.2]
Cell type			0.996			0.319
Serous	120	129.8 [121.0–138.6]		122	151.1 [141.6–160.6]
Others	45	129.7 [113.6–145.8]		45	142.2 [128.5–155.9]
Tumor grade			0.004			0.365
Well/Moderate	70	118.1 [106.9–129.2]		70	153.7 [141.3–166.0]
Poor	90	140.8 [130.1–151.4]		89	146.2 [135.3–157.0]
CA125			0.470			0.061
Negative	25	137.3 [116.2–158.4]		27	133.0 [119.1–147.0]
Positive	137	129.5 [121.1–137.8]		136	153.0 [144.1–161.9]
Chemosensitivity			0.112			0.254
Sensitive	144	129.6 [121.4–137.9]		147	149.6 [141.4–157.9]
Resistant	10	156.0 [116.0–195.9]		10	130.4 [86.3–174.4]

FIGO International Federation of Gynecology and Obstetrics, CI Confidence interval

ISSN: 1471-2407